Diamondbacks vs. Cubs Prediction, Odds, Picks - April 19

Data Skrive

Josh Naylor and the Arizona Diamondbacks hit the field on Saturday at Wrigley Field against Ben Brown, who is starting for the Chicago Cubs. First pitch is at 2:20 p.m. ET. The Diamondbacks are -112 moneyline favorites in this matchup against the Cubs (-106). Arizona is favored on the run line (-1.5 with +146 odds). The total for the matchup has been set at 7.5 runs.

Here is everything you need to know from a betting perspective on the Diamondbacks-Cubs game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Check out the best moments between the Chicago Cubs and the San Diego Padres.

Diamondbacks vs. Cubs Game Information & Odds

When: Saturday, April 19, 2025 at 2:20 p.m. ET
Where: Wrigley Field in Chicago, Illinois
How to watch on TV: MARQ and ARID

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Diamondbacks -112 -106 7.5 -110 -110 -1.5 +146 -178

Diamondbacks vs. Cubs Prediction

Score Prediction: Cubs 5, Diamondbacks 4
Total Prediction: Over 7.5 runs
Win Probabilities: Diamondbacks 55%, Cubs 45%

Diamondbacks vs. Cubs Betting Insights

This season, the Diamondbacks have been favored 16 times and won 10, or 62.5%, of those games.
Arizona has entered 16 games this season favored by -112 or more and is 10-6 in those contests.
Bookmakers have implied with the moneyline set for this matchup that the Diamondbacks have a 52.8% chance to win.
The Cubs have been underdogs in 12 games this season and have come away with the win five times (41.7%) in those contests.
This season, Chicago has been victorious five times in 11 chances when named as an underdog of at least -106 or worse on the moneyline.
Oddsmakers have implied with the moneyline set for this matchup that the Cubs have a 51.5% chance of pulling out a win.

Diamondbacks Recent Betting Performance

The Diamondbacks have a 6-3 record from the nine games they were favored on the moneyline over their last 10 matchups.
In their last 10 outings, the Diamondbacks and their opponents combined to go over the run total three times (all 10 games had set totals).
The Diamondbacks’ ATS record is 6-4-0 over their past 10 games.

Diamondbacks Recent Stats

Stat Avg/Total Record 7-3 Runs Per Game 5.0 HR 15 ERA 3.24 K/9 8.1

Diamondbacks Player Insights

Corbin Carroll leads the Diamondbacks with six home runs.
Among all MLB hitters, Carroll ranks 13th in batting average, 20th in on-base percentage, and fifth in slugging.
Carroll takes a hitting streak of 10 games into this matchup. In his last 10 outings he is batting .386 with five doubles, a triple, three home runs, two walks and 11 RBI.
Naylor has a club-leading .324 batting average.
Naylor is 28th in home runs and 23rd in RBI among all batters in the majors.
Naylor heads into this game looking for his sixth game in a row with a hit. During his last five outings he is hitting .333 with a double, three home runs, three walks and four RBI.
Geraldo Perdomo has racked up a team-best 18 runs batted in.
Perdomo is on a three-game hitting streak entering this contest. In his last five games he is hitting .267 with a home run, eight walks and five RBI.
Pavin Smith is batting .404 with seven doubles, three home runs and eight walks.
Smith has recorded at least one hit in four games in a row. During his last five outings he is hitting .438 with two doubles, two home runs, three walks and three RBI.

Cubs Recent Betting Performance

The Cubs have played as underdogs in five of their past 10 games and won two of those contests.
When it comes to hitting the over, the Cubs and their opponents are 6-4-0 in their last 10 games with a total.
The Cubs are 4-6-0 ATS over their last 10 games.

Cubs Recent Stats

Stat Avg/Total Record 5-5 Runs Per Game 5.4 HR 11 ERA 3.89 K/9 8.5

Cubs Player Insights

Kyle Tucker leads the Cubs with five long balls and runs batted in, driving in 19.
Tucker is 15th in home runs and fourth in RBI among all hitters in MLB.
Carson Kelly has a double, a triple, four home runs and 11 walks while batting .407.
Kelly is 28th overall in homers and 23rd in RBI this season.
Pete Crow-Armstrong is hitting .259 with six doubles, a triple, three home runs and five walks.
Seiya Suzuki is batting .290 with two doubles, a triple, four home runs and 11 walks.