The Red Sox’s season-opening road trip moves to Baltimore on Monday.

After dropping three of four to the Rangers in Texas, Boston will try to right the ship over a three-game set against the rival Orioles. The visitors will square off with left-hander Cade Povich in the opener, which marked the first start for a pair of reserves.

Rob Refsynder will take over in right field in place of the red-hot Wilyer Abreu, while Romy González will man first base in Triston Casas’ stead. The struggling Rafael Devers will remain in the Red Sox’s starting nine even with a southpaw on the hill for the O’s.

Povich will be opposed by Middleborough, Mass., native Sean Newcomb, who claimed the fifth spot in Boston’s season-opening rotation with a very strong spring training.

Here are the full lineups for Monday’s Red Sox-Orioles game, which has full coverage on NESN beginning at 1:30 p.m. ET.

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RED SOX (1-3)Jarren Duran, LFRafael Devers, DHAlex Bregman, 3BRob Refsnyder, RFTrevor Story, SSKristian Campbell, 2BRomy González, 1BConnor Wong, C

Ceddanne Rafaela, CF

Sean Newcomb, LHP (0-0, 0.00 ERA)

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ORIOLES (2-2)Jordan Westburg, 2BAdley Rutschman, CTyler O’Neill, LFRyan Mountcastle, 1BHeston Kjerstad, DHRamón Laureano, RFCedric Mullins, CFRamón Urías, 3B

Jackson Holliday, SS

Cade Povich, LHP (0-0, 0.00 ERA)

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Featured image via Raymond Carlin III/Imagn Images